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High-throughput analysis and protein engineering using microcapillary arrays

We describe a multi-purpose technology platform, termed μSCALE (Microcapillary Single Cell Analysis and Laser Extraction), that enables massively parallel, quantitative biochemical and biophysical measurements on millions of protein variants expressed from yeast or bacteria. μSCALE spatially segrega...

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Detalles Bibliográficos
Autores principales: Chen, Bob, Lim, Sungwon, Kannan, Arvind, Alford, Spencer C., Sunden, Fanny, Herschlag, Daniel, Dimov, Ivan K., Baer, Thomas M., Cochran, Jennifer R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215714/
https://www.ncbi.nlm.nih.gov/pubmed/26641932
http://dx.doi.org/10.1038/nchembio.1978