Elevated levels of brain homocysteine directly modulates the pathological phenotype of a mouse model of tauopathy

High circulating level of homocysteine (Hcy), also known as hyper-homocysteinemia, is a risk factor for Alzheimer’s disease (AD). Previous studies showed that elevated Hcy promotes brain amyloidosis and behavioral deficits in mouse models of AD. However, whether it also directly modulates the develo...

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Detalles Bibliográficos
Autores principales: Di Meco, Antonio, Li, Jian-Guo, Barrero, Carlos, Merali, Salim, Praticò, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215750/
https://www.ncbi.nlm.nih.gov/pubmed/29728702
http://dx.doi.org/10.1038/s41380-018-0062-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215750/
https://www.ncbi.nlm.nih.gov/pubmed/29728702
http://dx.doi.org/10.1038/s41380-018-0062-0

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