Transcriptome–pathology correlation identifies interplay between TDP-43 and the expression of its kinase CK1E in sporadic ALS

Sporadic amyotrophic lateral sclerosis (sALS) is the most common form of ALS, however, the molecular mechanisms underlying cellular damage and motor neuron degeneration remain elusive. To identify molecular signatures of sALS we performed genome-wide expression profiling in laser capture microdissec...

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Detalles Bibliográficos
Autores principales: Krach, Florian, Batra, Ranjan, Wheeler, Emily C., Vu, Anthony Q., Wang, Ruth, Hutt, Kasey, Rabin, Stuart J., Baughn, Michael W., Libby, Ryan T., Diaz-Garcia, Sandra, Stauffer, Jennifer, Pirie, Elaine, Saberi, Shahram, Rodriguez, Maria, Madrigal, Assael A., Kohl, Zacharias, Winner, Beate, Yeo, Gene W., Ravits, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215775/
https://www.ncbi.nlm.nih.gov/pubmed/29881994
http://dx.doi.org/10.1007/s00401-018-1870-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215775/
https://www.ncbi.nlm.nih.gov/pubmed/29881994
http://dx.doi.org/10.1007/s00401-018-1870-7

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