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Shorter telomeres associated with high doses of glucocorticoids: the link to increased mortality?

OBJECTIVE: Patients with non-functioning pituitary adenomas exhibit high morbidity and mortality rates. Growth hormone deficiency and high doses of glucocorticoid substitution therapy have been identified as corresponding risk factors. Interestingly, high levels of endogenous cortisol in, e.g., pati...

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Detalles Bibliográficos
Autores principales: Athanasoulia-Kaspar, Anastasia P, Auer, Matthias K, Stalla, Günter K, Jakovcevski, Mira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215799/
https://www.ncbi.nlm.nih.gov/pubmed/30352410
http://dx.doi.org/10.1530/EC-18-0362