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Elevated extracellular calcium ions promote proliferation and migration of mesenchymal stem cells via increasing osteopontin expression

Supplementation of mesenchymal stem cells (MSCs) at sites of bone resorption is required for bone homeostasis because of the non-proliferation and short lifespan properties of the osteoblasts. Calcium ions (Ca(2+)) are released from the bone surfaces during osteoclast-mediated bone resorption. Howev...

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Detalles Bibliográficos
Autores principales: Lee, Mi Nam, Hwang, Hee-Su, Oh, Sin-Hye, Roshanzadeh, Amir, Kim, Jung-Woo, Song, Ju Han, Kim, Eung-Sam, Koh, Jeong-Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215840/
https://www.ncbi.nlm.nih.gov/pubmed/30393382
http://dx.doi.org/10.1038/s12276-018-0170-6