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Sexually Dimorphic Regulation of EET Synthesis and Metabolism: Roles of Estrogen

Epoxyeicosatrienoic acids (EETs) are metabolites of arachidonic acid via cytochrome P450 (CYP)/epoxygenase and are hydrolyzed by soluble epoxide hydrolase (sEH). Circulating and tissue levels of EETs are controlled by CYP (EET synthesis) and sEH (EET degradation). Therefore, both increases in CYP ac...

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Detalles Bibliográficos
Autores principales: Huang, An, Sun, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215857/
https://www.ncbi.nlm.nih.gov/pubmed/30420806
http://dx.doi.org/10.3389/fphar.2018.01222