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Wnt signaling in human and mouse breast cancer: Focusing on Wnt ligands, receptors and antagonists

Wnt proteins, a group of secreted glycoproteins, mainly combine with receptors Frizzled (FZD) and/or low‐density‐lipoprotein receptor‐related proteins 5/6 (LRP5/6), initiating β‐catenin‐dependent and ‐independent signaling pathways. These pathways, which can be regulated by some secreted antagonists...

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Detalles Bibliográficos
Autores principales: Yin, Ping, Wang, Wei, Zhang, Zhongbo, Bai, Yu, Gao, Jian, Zhao, Chenghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215866/
https://www.ncbi.nlm.nih.gov/pubmed/30137666
http://dx.doi.org/10.1111/cas.13771