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BPR1J373, a novel multitargeted kinase inhibitor, effectively suppresses the growth of gastrointestinal stromal tumor

Gastrointestinal stromal tumor (GIST) is a type of KIT‐driven cancer. KIT gene mutations are found in approximately 80% of GISTs, and most of these mutations occur in exon 9 and exon 11. Imatinib has been successfully used as a first‐line treatment for advanced GIST, with a significant improvement i...

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Detalles Bibliográficos
Autores principales: Tsai, Hui‐Jen, Jiaang, Weir‐Torn, Shih, Neng‐Yao, Fletcher, Jonathan A., Lin, Ming‐Jon, Yang, Ming‐Yu, Chen, Chiung‐Tong, Hsu, Tsu‐An John, Wu, Chun‐Chieh, Lin, Hui‐You, Chen, Li‐Tzong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215875/
https://www.ncbi.nlm.nih.gov/pubmed/30142229
http://dx.doi.org/10.1111/cas.13773