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ROCK inhibitor enhances the growth and migration of BRAF‐mutant skin melanoma cells

Rho‐associated protein kinase (ROCK) plays crucial roles in the proliferation and migration of different types of cells. ROCK inhibitor Y‐27632 was previously reported to inhibit melanoma cell growth, and ROCK signaling was suggested to be a therapeutic target for treating melanoma. However, the neg...

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Detalles Bibliográficos
Autores principales: Chang, Fei, Zhang, Yunpeng, Mi, Jun, Zhou, Qian, Bai, Fuxiang, Xu, Xin, Fisher, David E., Sun, Qinfeng, Wu, Xunwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215891/
https://www.ncbi.nlm.nih.gov/pubmed/30168234
http://dx.doi.org/10.1111/cas.13786