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Recombinant human arginase induces apoptosis through oxidative stress and cell cycle arrest in small cell lung cancer

Small cell lung cancer (SCLC) accounts for approximately 13% of all lung cancer cases. Small cell lung cancer is characterized by frequent relapse, and current treatments lack tumor specificity. Arginine is a non‐essential amino acid for human normal cells but critical to some tumor cells that canno...

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Detalles Bibliográficos
Autores principales: Xu, Shi, Lam, Sze‐Kwan, Cheng, Paul Ning‐Man, Ho, James Chung‐Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215893/
https://www.ncbi.nlm.nih.gov/pubmed/30155941
http://dx.doi.org/10.1111/cas.13782