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Azithromycin treatment modifies airway and blood gene expression networks in neutrophilic COPD

Long-term, low-dose azithromycin reduces exacerbation frequency in chronic obstructive pulmonary disease (COPD), yet the mechanism remains unclear. This study characterised genome-wide gene expression changes in patients with neutrophilic COPD following long-term, low-dose azithromycin treatment. Pa...

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Detalles Bibliográficos
Autores principales: Baines, Katherine J., Wright, Thomas K., Gibson, Peter G., Powell, Heather, Hansbro, Philip M., Simpson, Jodie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215914/
https://www.ncbi.nlm.nih.gov/pubmed/30406125
http://dx.doi.org/10.1183/23120541.00031-2018