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Downregulation of PIM1 regulates glycolysis and suppresses tumor progression in gallbladder cancer

BACKGROUND: PIM1, a serine/threonine kinase, plays an essential role in tumorigenesis of multiple types of tumors. However, the expression pattern and functions of PIM1 in gallbladder cancer (GBC) remain largely unknown. MATERIALS AND METHODS: Immunohistochemistry, quantitative real-time PCR, and we...

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Detalles Bibliográficos
Autores principales: Xue, Chen, He, Yuting, Hu, Qiuyue, Yu, Yan, Chen, Xiaolong, Chen, Jianan, Ren, Fang, Li, Juan, Ren, Zhigang, Cui, Guangying, Sun, Ranran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215917/
https://www.ncbi.nlm.nih.gov/pubmed/30464610
http://dx.doi.org/10.2147/CMAR.S184381