Dipeptidyl peptidase 4 inhibitor anagliptin ameliorates hypercholesterolemia in hypercholesterolemic mice through inhibition of intestinal cholesterol transport

AIMS/INTRODUCTION: Recent data showed that dipeptidyl peptidase 4 (DPP‐4) inhibitors exert a lipid‐lowering effect in diabetes patients. However, the mechanism of action is not yet clearly understood. We investigated the effect of anagliptin on cholesterol metabolism and transport in the small intes...

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Detalles Bibliográficos
Autores principales: Goto, Moritaka, Furuta, Shinji, Yamashita, Satoko, Hashimoto, Hiroyuki, Yano, Wataru, Inoue, Noriyuki, Kato, Noriaki, Kaku, Kohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215941/
https://www.ncbi.nlm.nih.gov/pubmed/29754453
http://dx.doi.org/10.1111/jdi.12860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215941/
https://www.ncbi.nlm.nih.gov/pubmed/29754453
http://dx.doi.org/10.1111/jdi.12860

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