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How does glucagon‐like peptide 1 stimulate human β‐cell proliferation? A lesson from islet graft experiments
The incidence of type 2 diabetes increases with age. The age‐dependent decline in functional β‐cell mass contributes to the increased risk of onset of diabetes, reflecting the central role of pancreatic β‐cells in glucose homeostasis. Indeed, the replication rate of human and rodent β‐cells is known...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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John Wiley and Sons Inc.
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215945/ https://www.ncbi.nlm.nih.gov/pubmed/29770600 http://dx.doi.org/10.1111/jdi.12861 |