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How does glucagon‐like peptide 1 stimulate human β‐cell proliferation? A lesson from islet graft experiments

The incidence of type 2 diabetes increases with age. The age‐dependent decline in functional β‐cell mass contributes to the increased risk of onset of diabetes, reflecting the central role of pancreatic β‐cells in glucose homeostasis. Indeed, the replication rate of human and rodent β‐cells is known...

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Detalles Bibliográficos
Autor principal: Fujitani, Yoshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215945/
https://www.ncbi.nlm.nih.gov/pubmed/29770600
http://dx.doi.org/10.1111/jdi.12861