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A Conditional Dependency on MELK for the Proliferation of Triple-Negative Breast Cancer Cells

The role of maternal and embryonic leucine zipper kinase (MELK) in cancer cell proliferation has been contentious, with recent studies arriving at disparate conclusions. We investigated the in vitro dependency of cancer cells on MELK under a range of assay conditions. Abrogation of MELK expression h...

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Detalles Bibliográficos
Autores principales: Wang, Yubao, Li, Ben B., Li, Jing, Roberts, Thomas M., Zhao, Jean J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215964/
https://www.ncbi.nlm.nih.gov/pubmed/30391850
http://dx.doi.org/10.1016/j.isci.2018.10.015