Inducible Intestine-Specific Expression of kras(V12) Triggers Intestinal Tumorigenesis In Transgenic Zebrafish()

KRAS mutations are a major risk factor in colorectal cancers. In particular, a point mutation of KRAS of amino acid 12, such as KRAS(V12), renders it stable activity in oncogenesis. We found that kras(V12) promotes intestinal carcinogenesis by generating a transgenic zebrafish line with inducible kr...

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Detalles Bibliográficos
Autores principales: Lu, Jeng-Wei, Raghuram, Divya, Fong, Pei-Shi Angelina, Gong, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215966/
https://www.ncbi.nlm.nih.gov/pubmed/30390498
http://dx.doi.org/10.1016/j.neo.2018.10.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215966/
https://www.ncbi.nlm.nih.gov/pubmed/30390498
http://dx.doi.org/10.1016/j.neo.2018.10.002

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