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Inducible Intestine-Specific Expression of kras(V12) Triggers Intestinal Tumorigenesis In Transgenic Zebrafish()
KRAS mutations are a major risk factor in colorectal cancers. In particular, a point mutation of KRAS of amino acid 12, such as KRAS(V12), renders it stable activity in oncogenesis. We found that kras(V12) promotes intestinal carcinogenesis by generating a transgenic zebrafish line with inducible kr...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Neoplasia Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215966/ https://www.ncbi.nlm.nih.gov/pubmed/30390498 http://dx.doi.org/10.1016/j.neo.2018.10.002 |