Losartan Alleviates Renal Fibrosis and Inhibits Endothelial-to-Mesenchymal Transition (EMT) Under High-Fat Diet-Induced Hyperglycemia

The endothelial-to-mesenchymal transition (EMT) of glomerular vascular endothelial cells is considered to be pivotal in diabetic nephropathy (DN). The risk of DN can be decreased by losartan, but the potential molecular mechanism(s) are not fully understood. Extensive data show that the EMT occurs i...

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Detalles Bibliográficos
Autores principales: Yao, Yufeng, Li, Yong, Zeng, Xiaofei, Ye, Zheng, Li, Xia, Zhang, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215973/
https://www.ncbi.nlm.nih.gov/pubmed/30420805
http://dx.doi.org/10.3389/fphar.2018.01213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215973/
https://www.ncbi.nlm.nih.gov/pubmed/30420805
http://dx.doi.org/10.3389/fphar.2018.01213

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