Onset of deaminase APOBEC3B induction in response to DNA double-strand breaks

Deamination of 5-methyl cytosine is a major cause of cancer-driver mutations in inflammation-associated cancers. The deaminase APOBEC3B is expressed in these cancers and causes mutations under replication stress; however, the mechanisms by which APOBEC3B mediates deamination and its association with...

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Detalles Bibliográficos
Autores principales: Shimizu, Atsuhiro, Fujimori, Haruka, Minakawa, Yusuke, Matsuno, Yusuke, Hyodo, Mai, Murakami, Yasufumi, Yoshioka, Ken-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216020/
https://www.ncbi.nlm.nih.gov/pubmed/30417129
http://dx.doi.org/10.1016/j.bbrep.2018.10.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216020/
https://www.ncbi.nlm.nih.gov/pubmed/30417129
http://dx.doi.org/10.1016/j.bbrep.2018.10.010

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