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An Abies procera-derived tetracyclic triterpene containing a steroid-like nucleus core and a lactone side chain attenuates in vitro survival of both Fasciola hepatica and Schistosoma mansoni

Two economically and biomedically important platyhelminth species, Fasciola hepatica (liver fluke) and Schistosoma mansoni (blood fluke), are responsible for the neglected tropical diseases (NTDs) fasciolosis and schistosomiasis. Due to the absence of prophylactic vaccines, these NTDs are principall...

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Detalles Bibliográficos
Autores principales: Whiteland, Helen L., Chakroborty, Anand, Forde-Thomas, Josephine E., Crusco, Alessandra, Cookson, Alan, Hollinshead, Jackie, Fenn, Caroline A., Bartholomew, Barbara, Holdsworth, Peter A., Fisher, Maggie, Nash, Robert J., Hoffmann, Karl F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216039/
https://www.ncbi.nlm.nih.gov/pubmed/30399512
http://dx.doi.org/10.1016/j.ijpddr.2018.10.009