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An Abies procera-derived tetracyclic triterpene containing a steroid-like nucleus core and a lactone side chain attenuates in vitro survival of both Fasciola hepatica and Schistosoma mansoni
Two economically and biomedically important platyhelminth species, Fasciola hepatica (liver fluke) and Schistosoma mansoni (blood fluke), are responsible for the neglected tropical diseases (NTDs) fasciolosis and schistosomiasis. Due to the absence of prophylactic vaccines, these NTDs are principall...
Autores principales: | Whiteland, Helen L., Chakroborty, Anand, Forde-Thomas, Josephine E., Crusco, Alessandra, Cookson, Alan, Hollinshead, Jackie, Fenn, Caroline A., Bartholomew, Barbara, Holdsworth, Peter A., Fisher, Maggie, Nash, Robert J., Hoffmann, Karl F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216039/ https://www.ncbi.nlm.nih.gov/pubmed/30399512 http://dx.doi.org/10.1016/j.ijpddr.2018.10.009 |
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