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Simvastatin Protects Heart from Pressure Overload Injury by Inhibiting Excessive Autophagy

Cardiac hypertrophy is an independent predictor of cardiovascular morbidity and mortality. To identify the mechanisms by which simvastatin inhibits cardiac hypertrophy induced by pressure overload, we determined effects of simvastatin on 14-3-3 protein expression and autophagic activity. Simvastatin...

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Detalles Bibliográficos
Autores principales: Su, Feifei, Shi, Miaoqian, Zhang, Jian, Zheng, Qiangsun, Zhang, Dongwei, Zhang, Wei, Wang, Haichang, Li, Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216062/
https://www.ncbi.nlm.nih.gov/pubmed/30443172
http://dx.doi.org/10.7150/ijms.28106