Doublecortin-like kinase 1 compromises DNA repair and induces chromosomal instability

Doublecortin-like kinase 1 (DCLK1) is a serine/threonine-kinase with two doublecortin (DCX) domains. DCLK1 is associated with microtubules via DCX domains and regulates microtubule polymerization. DCLK1 is known to be expressed in cancer stem cells and provides cancer cells with tumor-initiating cap...

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Detalles Bibliográficos
Autores principales: Lu, Yuxiong, Maruyama, Junichi, Kuwata, Keiko, Fukuda, Hiroyuki, Iwasa, Hiroaki, Arimoto-Matsuzaki, Kyoko, Sugimura, Haruhiko, Hata, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216093/
https://www.ncbi.nlm.nih.gov/pubmed/30417131
http://dx.doi.org/10.1016/j.bbrep.2018.10.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216093/
https://www.ncbi.nlm.nih.gov/pubmed/30417131
http://dx.doi.org/10.1016/j.bbrep.2018.10.014

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