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P-FN12, an H4R-Based Epitope Vaccine Screened by Phage Display, Regulates the Th1/Th2 Balance in Rat Allergic Rhinitis

Allergic rhinitis (AR) involves antigen-specific immune-inflammation of the nasal mucosa. Classical therapy for AR targets the histamine pathway, e.g., histamine receptor blockers. Histamine H4 receptor (H4R) was suggested as a novel therapeutic target due to its wide expression on almost all immune...

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Detalles Bibliográficos
Autores principales: Wang, Yuqian, Sha, Jichao, Wang, Heng, An, Lifeng, Liu, Tie, Li, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216098/
https://www.ncbi.nlm.nih.gov/pubmed/30417023
http://dx.doi.org/10.1016/j.omtm.2018.09.004