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The Toll-Like Receptor 2 agonist PEG-Pam(2)Cys as an immunochemoprophylactic and immunochemotherapeutic against the liver and transmission stages of malaria parasites

Both vaccine and therapeutic approaches to malaria are based on conventional paradigms; whole organism or single antigen epitope-based vaccines administered with or without an adjuvant, and chemotherapeutics (anti-malaria drugs) that are toxic to the parasite. Two major problems that limit the effec...

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Detalles Bibliográficos
Autores principales: Ernest, Medard, Hunja, Carol, Arakura, Yuka, Haraga, Yohei, Abkallo, Hussein M., Zeng, Weiguang, Jackson, David C., Chua, Brendon, Culleton, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216107/
https://www.ncbi.nlm.nih.gov/pubmed/30396012
http://dx.doi.org/10.1016/j.ijpddr.2018.10.006