Tamoxifen inhibits the biosynthesis of inositolphosphorylceramide in Leishmania

Previous work from our group showed that tamoxifen, an oral drug that has been in use for the treatment of breast cancer for over 40 years, is active both in vitro and in vivo against several species of Leishmania, the etiological agent of leishmaniasis. Using a combination of metabolic labeling wit...

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Detalles Bibliográficos
Autores principales: Trinconi, Cristiana T., Miguel, Danilo C., Silber, Ariel M., Brown, Christopher, Mina, John G.M., Denny, Paul W., Heise, Norton, Uliana, Silvia R.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Regular article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216108/
https://www.ncbi.nlm.nih.gov/pubmed/30399513
http://dx.doi.org/10.1016/j.ijpddr.2018.10.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216108/
https://www.ncbi.nlm.nih.gov/pubmed/30399513
http://dx.doi.org/10.1016/j.ijpddr.2018.10.007

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