In silico drug screening by using genome-wide association study data repurposed dabrafenib, an anti-melanoma drug, for Parkinson’s disease

Parkinson’s disease (PD) is a neurodegenerative disorder characterized by dopaminergic neuron loss. At present, there are no drugs that stop the progression of PD. As with other multifactorial genetic disorders, genome-wide association studies (GWASs) found multiple risk loci for PD, although their...

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Detalles Bibliográficos
Autores principales: Uenaka, Takeshi, Satake, Wataru, Cha, Pei-Chieng, Hayakawa, Hideki, Baba, Kousuke, Jiang, Shiying, Kobayashi, Kazuhiro, Kanagawa, Motoi, Okada, Yukinori, Mochizuki, Hideki, Toda, Tatsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Association Studies Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216208/
https://www.ncbi.nlm.nih.gov/pubmed/30137437
http://dx.doi.org/10.1093/hmg/ddy279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216208/
https://www.ncbi.nlm.nih.gov/pubmed/30137437
http://dx.doi.org/10.1093/hmg/ddy279

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