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Uncovering Natural Longevity Alleles from Intercrossed Pools of Aging Fission Yeast Cells

Quantitative traits often show large variation caused by multiple genetic factors . One such trait is the chronological lifespan of non-dividing yeast cells, serving as a model for cellular aging. Screens for genetic factors involved in aging typically assay mutants of protein-coding genes. To ident...

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Detalles Bibliográficos
Autores principales: Ellis, David A., Mustonen, Ville, Rodríguez-López, María, Rallis, Charalampos, Malecki, Michał, Jeffares, Daniel C., Bähler, Jürg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216586/
https://www.ncbi.nlm.nih.gov/pubmed/30072377
http://dx.doi.org/10.1534/genetics.118.301262