Functional and Molecular Characterization of C91S Mutation in the Second Epidermal Growth Factor-Like Domain of Factor VII

BACKGROUND: Coagulation Factor VII is a vitamin K-dependent serine protease which has a pivotal role in the initiation of the coagulation cascade. The congenital Factor VII deficiency is a recessive hemorrhagic disorder that occurs due to mutations of F7 gene. In the present study C91S (p.C91S) subs...

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Detalles Bibliográficos
Autores principales: Mashayekhi, Amir, Shahbazi, Shirin, Omrani, Mirdavood
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Genetic Engineering and Biotechnology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217260/
https://www.ncbi.nlm.nih.gov/pubmed/30555841
http://dx.doi.org/10.21859/ijb.1813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217260/
https://www.ncbi.nlm.nih.gov/pubmed/30555841
http://dx.doi.org/10.21859/ijb.1813

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