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Optimization of EnBase Fed-Batch Cultivation to Improve Soluble Fraction Ratio of α-Luffin Ribosome Inactivating Protein

BACKGROUND: The increase of the protein expression via ribosomal manipulation is one of the suggested cellular mechanisms involved in EnBase fed-batch mode of cultivation. However, this system has not been implemented for cytotoxic proteins. OBJECTIVES: Here, the expression pattern of α-Luffin, a ri...

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Detalles Bibliográficos
Autores principales: Barkhordari, Farzaneh, Raigani, Mozhgan, Garoosi, Yeganeh Talebkhan, Mahboudi, Fereidoun, Davami, Fatemeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Genetic Engineering and Biotechnology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217263/
https://www.ncbi.nlm.nih.gov/pubmed/30555837
http://dx.doi.org/10.21859/ijb.1482