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Ribonuclease activity of MARF1 controls oocyte RNA homeostasis and genome integrity in mice

Producing normal eggs for fertilization and species propagation requires completion of meiosis and protection of the genome from the ravages of retrotransposons. Mutation of Marf1 (meiosis regulator and mRNA stability factor 1) results in defects in both these key processes in mouse oocytes and thus...

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Detalles Bibliográficos
Autores principales: Yao, Qingqing, Cao, Guangyi, Li, Mingzhe, Wu, Baixing, Zhang, Xiaoyun, Zhang, Teng, Guo, Jing, Yin, Hong, Shi, Lanying, Chen, Jiayi, Yu, Xiang, Zheng, Lina, Ma, Jinbiao, Su, You-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217404/
https://www.ncbi.nlm.nih.gov/pubmed/30333187
http://dx.doi.org/10.1073/pnas.1809744115