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Ribonuclease activity of MARF1 controls oocyte RNA homeostasis and genome integrity in mice
Producing normal eggs for fertilization and species propagation requires completion of meiosis and protection of the genome from the ravages of retrotransposons. Mutation of Marf1 (meiosis regulator and mRNA stability factor 1) results in defects in both these key processes in mouse oocytes and thus...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217404/ https://www.ncbi.nlm.nih.gov/pubmed/30333187 http://dx.doi.org/10.1073/pnas.1809744115 |