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Al(18)F-NODA Benzothiazole Derivatives as Imaging Agents for Cerebrovascular Amyloid in Cerebral Amyloid Angiopathy

[Image: see text] In this study, we synthesized four novel Al(18/19)F-labeled 2-phenylbenzothiazole derivatives conjugated to 1,4,7-triazacyclononane-1,4-diacetic acid via alkyl linkers and evaluated them as imaging agent targets to amyloid-β (Aβ) plaques deposited in the blood vessels of cerebral a...

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Detalles Bibliográficos
Autores principales: Song, Jia, Peng, Xiaohui, Li, Linlin, Yang, Fan, Zhang, Xiaojun, Zhang, Jinming, Dai, Jiapei, Cui, Mengchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217595/
https://www.ncbi.nlm.nih.gov/pubmed/30411027
http://dx.doi.org/10.1021/acsomega.8b01120