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Binding Analysis of the Inositol-Requiring Enzyme 1 Kinase Domain
[Image: see text] Inositol-requiring enzyme 1 (IRE1) is an orchestrator of the unfolded protein response (UPR), the cellular response to endoplasmic reticulum (ER) stress that plays a crucial role in tumor development. IRE1 signaling is the most evolutionary conserved branch of the UPR. Under ER str...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217623/ https://www.ncbi.nlm.nih.gov/pubmed/30411035 http://dx.doi.org/10.1021/acsomega.8b01404 |