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Binding Analysis of the Inositol-Requiring Enzyme 1 Kinase Domain

[Image: see text] Inositol-requiring enzyme 1 (IRE1) is an orchestrator of the unfolded protein response (UPR), the cellular response to endoplasmic reticulum (ER) stress that plays a crucial role in tumor development. IRE1 signaling is the most evolutionary conserved branch of the UPR. Under ER str...

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Detalles Bibliográficos
Autores principales:	Carlesso, Antonio, Chintha, Chetan, Gorman, Adrienne M., Samali, Afshin, Eriksson, Leif A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2018
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217623/ https://www.ncbi.nlm.nih.gov/pubmed/30411035 http://dx.doi.org/10.1021/acsomega.8b01404

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