Tuning the Balance between Fibrillation and Oligomerization of α-Synuclein in the Presence of Dopamine

[Image: see text] The aggregates of α-synuclein bear a close connection with Parkinson’s disease, which is largely characterized by the loss of the dopaminergic neurons. Dopamine promotes the formation of undesirable sodium dodecyl sulfate (SDS)-resistant oligomers of α-synuclein. In this study, we...

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Detalles Bibliográficos
Autores principales: Saha, Shivnetra, Khan, Mohammad Ashhar Iqbal, Mudhara, Deepak, Deep, Shashank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217689/
https://www.ncbi.nlm.nih.gov/pubmed/30411062
http://dx.doi.org/10.1021/acsomega.8b00993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217689/
https://www.ncbi.nlm.nih.gov/pubmed/30411062
http://dx.doi.org/10.1021/acsomega.8b00993

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