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A Phase I, Randomized, Double-Blind, Laser-Evoked Potential Study to Evaluate the Analgesic/Antihyperalgesic Effect of ASP9226, a State-Dependent N-Type Voltage-Gated Calcium Channel Inhibitor, in Healthy Male Subjects

OBJECTIVE: Evaluate the analgesic/antihyperalgesic effects of ASP9226, a state-dependent N-type voltage-gated calcium channel inhibitor, in healthy male subjects. DESIGN: Randomized, double-blind, double-dummy, placebo- and active comparator–controlled crossover study. SETTING: HPR Dr. Schaffler Gmb...

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Detalles Bibliográficos
Autores principales: Schaffler, Klaus, He, Weizhong, Passier, Paul, Tracy, Katherine, Fakhoury, Allam, Paul, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217710/
https://www.ncbi.nlm.nih.gov/pubmed/29378016
http://dx.doi.org/10.1093/pm/pnx338