TLR4 inhibitor TAK-242 attenuates the adverse neural effects of diet-induced obesity

BACKGROUND: Obesity exerts negative effects on brain health, including decreased neurogenesis, impaired learning and memory, and increased risk for Alzheimer’s disease and related dementias. Because obesity promotes glial activation, chronic neuroinflammation, and neural injury, microglia are implic...

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Detalles Bibliográficos
Autores principales: Moser, V. Alexandra, Uchoa, Mariana F., Pike, Christian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217784/
https://www.ncbi.nlm.nih.gov/pubmed/30396359
http://dx.doi.org/10.1186/s12974-018-1340-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217784/
https://www.ncbi.nlm.nih.gov/pubmed/30396359
http://dx.doi.org/10.1186/s12974-018-1340-0

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