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Alpha‐Synuclein Modulates the Physical Properties of DNA

Fundamental research on Parkinson's disease (PD) most often focuses on the ability of α‐synuclein (aS) to form oligomers and amyloids, and how such species promote brain cell death. However, there are indications that aS also plays a gene‐regulatory role in the cell nucleus. Here, the interacti...

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Detalles Bibliográficos
Autores principales: Jiang, Kai, Rocha, Sandra, Westling, Alvina, Kesarimangalam, Sriram, Dorfman, Kevin D., Wittung‐Stafshede, Pernilla, Westerlund, Fredrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217799/
https://www.ncbi.nlm.nih.gov/pubmed/30102440
http://dx.doi.org/10.1002/chem.201803933