Generation and characterization of two human induced pluripotent stem cell (hiPSC) lines homozygous for the Apolipoprotein e4 (APOE4) risk variant—Alzheimer's disease (ASUi005-A) and healthy non-demented control (ASUI006-A)

Although the majority of late-onset Alzheimer's disease (AD) patients are labeled sporadic, multiple genetic risk variants have been identified, the most powerful and prevalent of which is the e4 variant of the Apolipoprotein E (APOE) gene. Here, we generated human induced pluripotent stem cell...

Descripción completa

Detalles Bibliográficos
Autores principales: Brookhouser, Nicholas, Zhang, Ping, Caselli, Richard, Kim, Jean J., Brafman, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217860/
https://www.ncbi.nlm.nih.gov/pubmed/30296667
http://dx.doi.org/10.1016/j.scr.2018.09.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217860/
https://www.ncbi.nlm.nih.gov/pubmed/30296667
http://dx.doi.org/10.1016/j.scr.2018.09.007

Ejemplares similares