Differential Gene Expression in Macrophages From Human Atherosclerotic Plaques Shows Convergence on Pathways Implicated by Genome-Wide Association Study Risk Variants

OBJECTIVE—: Plaque macrophages are intricately involved in atherogenesis and plaque destabilization. We sought to identify functional pathways in human plaque macrophages that are differentially regulated in respect of (1) plaque stability and (2) lipid content. We hypothesized that differentially r...

Descripción completa

Detalles Bibliográficos
Autores principales: Chai, Joshua T., Ruparelia, Neil, Goel, Anuj, Kyriakou, Theodosios, Biasiolli, Luca, Edgar, Laurienne, Handa, Ashok, Farrall, Martin, Watkins, Hugh, Choudhury, Robin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Translational Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217969/
https://www.ncbi.nlm.nih.gov/pubmed/30354237
http://dx.doi.org/10.1161/ATVBAHA.118.311209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217969/
https://www.ncbi.nlm.nih.gov/pubmed/30354237
http://dx.doi.org/10.1161/ATVBAHA.118.311209

Ejemplares similares