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Data-driven, voxel-based analysis of brain PET images: Application of PCA and LASSO methods to visualize and quantify patterns of neurodegeneration

Spatial patterns of radiotracer binding in positron emission tomography (PET) images may convey information related to the disease topology. However, this information is not captured by the standard PET image analysis that quantifies the mean radiotracer uptake within a region of interest (ROI). On...

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Detalles Bibliográficos
Autores principales: Klyuzhin, Ivan S., Fu, Jessie F., Hong, Andy, Sacheli, Matthew, Shenkov, Nikolay, Matarazzo, Michele, Rahmim, Arman, Stoessl, A. Jon, Sossi, Vesna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218048/
https://www.ncbi.nlm.nih.gov/pubmed/30395576
http://dx.doi.org/10.1371/journal.pone.0206607