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Loss of BAP1 expression is associated with genetic mutation and can predict outcomes in gallbladder cancer

BACKGROUND: BRCA-1 associated protein (BAP1) is a de-ubiquitinating enzyme that regulates gene expression. Recently, the BAP1 mutation and its involvement in cancer survival have been reported in a range of tumor types, including uveal melanoma, mesothelioma, renal cancers, and biliary tract cancers...

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Detalles Bibliográficos
Autores principales: Hirosawa, Takashi, Ishida, Masaharu, Ishii, Kentaro, Kanehara, Keigo, Kudo, Katsuyoshi, Ohnuma, Shinobu, Kamei, Takashi, Motoi, Fuyuhiko, Naitoh, Takeshi, Selaru, Florin M., Unno, Michiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218052/
https://www.ncbi.nlm.nih.gov/pubmed/30395583
http://dx.doi.org/10.1371/journal.pone.0206643