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Nasal immunization with recombinant chimeric pneumococcal protein and cell wall from immunobiotic bacteria improve resistance of infant mice to Streptococcus pneumoniae infection

Respiratory tract infections and invasive disease caused by Streptococcus pneumoniae in high-risk groups are a major global health problem. Available human vaccines have reduced immunogenicity and low immunological memory in these populations, as well as high cost as a public health strategy in poor...

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Detalles Bibliográficos
Autores principales: Laiño, Jonathan, Villena, Julio, Suvorov, Alexander, Zelaya, Hortensia, Ortiz Moyano, Ramiro, Salva, Susana, Alvarez, Susana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218053/
https://www.ncbi.nlm.nih.gov/pubmed/30395582
http://dx.doi.org/10.1371/journal.pone.0206661