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Nasal immunization with recombinant chimeric pneumococcal protein and cell wall from immunobiotic bacteria improve resistance of infant mice to Streptococcus pneumoniae infection
Respiratory tract infections and invasive disease caused by Streptococcus pneumoniae in high-risk groups are a major global health problem. Available human vaccines have reduced immunogenicity and low immunological memory in these populations, as well as high cost as a public health strategy in poor...
Autores principales: | Laiño, Jonathan, Villena, Julio, Suvorov, Alexander, Zelaya, Hortensia, Ortiz Moyano, Ramiro, Salva, Susana, Alvarez, Susana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218053/ https://www.ncbi.nlm.nih.gov/pubmed/30395582 http://dx.doi.org/10.1371/journal.pone.0206661 |
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