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Metformin Use Associated with Reduced Risk of Dementia in Patients with Diabetes: A Systematic Review and Meta-Analysis

BACKGROUND: Metformin, a first line antihyperglycemic medication, is an AMPK activator and has been hypothesized to act as a geroprotective agent. Studies on its association with various classifications of age-related cognitive decline have shown mixed results with positive and negative findings. OB...

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Detalles Bibliográficos
Autores principales: Campbell, Jared M., Stephenson, Matthew D., de Courten, Barbora, Chapman, Ian, Bellman, Susan M., Aromataris, Edoardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218120/
https://www.ncbi.nlm.nih.gov/pubmed/30149446
http://dx.doi.org/10.3233/JAD-180263