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Clinical Experience with Cerebrospinal Fluid Aβ(42), Total and Phosphorylated Tau in the Evaluation of 1,016 Individuals for Suspected Dementia

BACKGROUND: Elevated total tau (tTau), 181-phosphorylated phosphorylated tau (pTau), and low amyloid-β(42) (Aβ(42)) in cerebrospinal fluid (CSF) represent a diagnostic biomarker for Alzheimer’s disease (AD). OBJECTIVE: The goal was to determine the overall accuracy of CSF Aβ(42), tTau, pTau, and the...

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Detalles Bibliográficos
Autores principales: Tariciotti, Leonardo, Casadei, Matthew, Honig, Lawrence S., Teich, Andrew F., McKhann II, Guy M., Tosto, Giuseppe, Mayeux, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218126/
https://www.ncbi.nlm.nih.gov/pubmed/30149454
http://dx.doi.org/10.3233/JAD-180548