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Pharmacokinetics in Rat of P8, a Peptide Drug Candidate for the Treatment of Alzheimer’s Disease: Stability and Delivery to the Brain(1)

Strategies to achieve a therapy for Alzheimer’s disease (AD) aimed at reducing the effects of amyloid-β (Aβ) have largely involved inhibiting or modifying the activities of the β- or γ-secretases or by the use of monoclonal antibodies (MAb). We previously offered the potential for a new, early and e...

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Detalles Bibliográficos
Autores principales: Dewji, Nazneen N., Azar, Marc R., Hanson, Leah R., Frey II, William H., Morimoto, Bruce H., Johnson, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218153/
https://www.ncbi.nlm.nih.gov/pubmed/30480260
http://dx.doi.org/10.3233/ADR-180078