Apoptosis signal-regulating kinase 1 (ASK1) inhibition attenuates human airway smooth muscle growth and migration in chronic obstructive pulmonary disease (COPD)

Increased airway smooth muscle (ASM) mass is observed in chronic obstructive pulmonary disease (COPD) which is correlated with disease severity and negatively impact lung function in these patients. Thus, there is clear unmet clinical need for finding new therapies which can target airway remodeling...

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Detalles Bibliográficos
Autores principales: Eapen, Mathew S, Kota, Anudeep, Vindin, Howard, McAlinden, Kielan D, Xenaki, Dia, Oliver, Brian G, Deshpande, Deepak A, Sohal, Sukhwinder Singh, Sharma, Pawan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218165/
https://www.ncbi.nlm.nih.gov/pubmed/30006481
http://dx.doi.org/10.1042/CS20180398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218165/
https://www.ncbi.nlm.nih.gov/pubmed/30006481
http://dx.doi.org/10.1042/CS20180398

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