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Therapeutic Effect on Bladder Cancer with a Conditionally Replicating Oncolytic Virus Derived from Type II Herpes Simplex Virus

PURPOSE: Despite recent improvements, resistance to traditional immunotherapy or chemotherapy is still common in patients with bladder cancer. We constructed an oncolytic virus from herpes simplex virus type II (HSV-2), which selectively targets tumor cells with an activated Ras signaling pathway. W...

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Detalles Bibliográficos
Autores principales: Joo, Kwan Joong, Li, Hongtao, Zhang, Xiaoliu, Lerner, Seth P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218184/
https://www.ncbi.nlm.nih.gov/pubmed/30561438
http://dx.doi.org/10.3233/BLC-150013