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Multiple Mechanisms Inactivate the LIN-41 RNA-Binding Protein To Ensure a Robust Oocyte-to-Embryo Transition in Caenorhabditis elegans

In the nematode Caenorhabditis elegans, the conserved LIN-41 RNA-binding protein is a translational repressor that coordinately controls oocyte growth and meiotic maturation. LIN-41 exerts these effects, at least in part, by preventing the premature activation of the cyclin-dependent kinase CDK-1. H...

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Detalles Bibliográficos
Autores principales: Spike, Caroline A., Huelgas-Morales, Gabriela, Tsukamoto, Tatsuya, Greenstein, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218228/
https://www.ncbi.nlm.nih.gov/pubmed/30206186
http://dx.doi.org/10.1534/genetics.118.301421